Description: Telmisartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin by selectively blocking the binding of angiotensin to the AT1, receptor in many tissues, such as vascular smooth muscle and the adrenal gland. Its action is therefore independent of the pathways for angiotensin synthesis.
Indication:
NADSAR H (Telmisartan/Hydrochlorothiazide) tablets are indicated for the treatment of hypertension, alone or with other antihypertensive agents. NADSAR H tablets may also be used as initial therapy in patients who are likely to need multiple drugs to achieve their blood pressure goals. Patients with moderate or severe hypertension are at relatively high risk for cardiovascular events (such as strokes, heart attacks, and heart failure), kidney failure, and vision problems, so prompt treatment is clinically relevant.