Description: Vonoprazan is a potassium competitive acid blocker (PCAB) and inhibits H+, K+-ATPase in a reversible and potassium-competitive manner used for the treatment of gastric ulcer, duodenal ulcer, or reflux esopha-gitis.
Indication:
Treatment of gastric ulcer (GU).
Treatment of duodenal ulcer (DU).
Treatment of reflux esophagitis (RE) (erosive esophagitis EE).
Maintenance treatment of reflux esophagitis (erosive esophagitis) in patients with repeat recurrence and relapse of the condition.
Prevention of recurrence of gastric ulcer or duodenal ulcer during NSAIDs administration.
Adjunct to Helicobacter pylori eradication associated with: Gastric ulcer, duodenal ulcer, gastric MALT lymphoma, idiopathic thrombocytopenic purpura, the stomach after endoscopic resection of early stage cancer, or Helicobacter pylori gastritis.